Fentanyl-driven overdoses increasing

Drug overdose deaths in Oregon more than doubled between 2019 and 2021, with the increase driven largely by misuse of the powerful synthetic opioid fentanyl, an Oregon Health Authority (OHA) analysis has found. Preliminary data indicate that this trend has continued in 2022.

Over the last 30 months, fentanyl has become a leading cause of overdose deaths, particularly among people who don’t have access to harm-reduction services. This trend is prompting urgent requests for supplies of naloxone, the rescue drug that rapidly reverses an opioid overdose.

“We are seeing a critical need for naloxone as many communities experience dramatic increases in overdoses due to fentanyl misuse,” said Dean Sidelinger, MD, MSEd, health officer and state epidemiologist at OHA. He noted that many counties have reported multiple opioid overdoses over the last several weeks, and that there has been a corresponding demand for naloxone. “We encourage everyone in Oregon to educate themselves and their loved ones — including young people — about the importance of naloxone, how to use it in an overdose emergency, and where people can access it.”

In 2021, nearly a third of Oregon’s counties saw more people die from fentanyl overdose than overdose from any other drug, OHA analysts found.

An overdose is always a medical emergency. Individuals should call 911 immediately after administering naloxone, and be aware that it may take multiple doses of naloxone to reverse the overdose. Oregon’s Good Samaritan law protects the caller and the person who has overdosed against possession and paraphernalia charges.

People who are taking prescription opioids should ask their health care provider or pharmacist for a naloxone prescription.

Health insurance may cover the cost of naloxone.

Individuals who want to have naloxone on hand for someone else should ask their pharmacist for a prescription.

While health insurance usually will not cover this, coupons may be available online to offset the cost.

OHA’s Naloxone Rescue for Opioid Overdose webpage contains naloxone frequently asked questions and a map showing Oregon pharmacies that distribute the medicine.

Anyone actively using opioids, or other illicit substances, can get naloxone and other harm-reduction materials at no cost through syringe service programs.

Syringe service programs are available to anyone who uses drugs, regardless of whether they inject them.

In addition, OHA is issuing the following warnings to people who use drugs:

• Unless a pharmacist directly hands you a prescription pill, assume it is counterfeit and contains fentanyl.

• Assume any pills obtained from the internet or a friend are counterfeit and contain fentanyl.

• If you are using pills, don’t use alone. Always have naloxone on hand and visible.

• Test your drugs with fentanyl test strips before you use them. Fentanyl test strips can often be accessed at local harm-reduction sites.

A review of State Unintentional Drug Overdose Reporting System and Oregon death certificate data by analysts from OHA’s Injury and Violence Prevention Section found that unintentional/undetermined drug overdose deaths increased from 496 in 2019 to 1,072 in 2021. The 2021 figure doesn’t include all fourth-quarter overdose deaths which are still being tallied and analyzed.

Unintentional/undetermined fentanyl overdose deaths jumped more than 600 percent between 2019 and 2021, from 71 to 509, respectively. Of unintentional/undetermined drug overdose deaths in 2021, 47.5 percent were due to fentanyl; in 2020, fentanyl caused 32.1 percent of overdose deaths; in 2019, the drug was responsible for 14.3 percent of overdoses.

Overall, unintentional/undetermined overdoses from opioids, including fentanyl and heroin, rose from 280 to 739 deaths — a 164 percent increase.